Since the early 20th century, ultraviolet germicidal irradiation has been studied and used for the disinfection of microorganisms. Microbes are uniquely vulnerable to the effects of UV light at specific wavelengths that contain just the right amout of energy to break down organic molecular bonds.

Vioguard's keyboard uses high power germicidal ultraviolet light, otherwise known as UV-C, at 254 nm wavelength. Recent advances in lamp and electronic ballast technology have made it possible to provide high power levels combined with long lamp life, which means the bulbs will last for many months even in the heaviest possible use cases.

The keyboard uses two 25-watt UV-C lamps with a reflector and diffuser to distribute the light evenly. Based on published data, this level of UV-C will kill more than 99.99% of harmful microorganisms such as MRSA, mold, and other contaminants within seconds.